ATX code: А05С





Trade name of the drug : Livson

Active ingredient (INN) : phospholipids

Dosage form : solution for injection


One ampoule contains:

active substance : phosphodithylcholine from soybeans (3 sn-phosphodityl) choline makes up 93% of total phosphodithylcholine (synonym – “essential phospholipids”, EPL) 250 mg.

excipients : benzyl alcohol, sodium chloride, sodium hydroxide solution (20%), water for injection.

Description : yellow homogeneous transparent solution.

Pharmacotherapeutic group:  hepatoprotector.

Code ATH:  A05S


Pharmacological properties

The hepatoprotective effect is due to the properties of the components included in the drug.

“Essential phospholipids” are complex substances that are diglyceride esters of phosphatidic and unsaturated fatty acids (mainly oleic and linoleic). They are an important structural element of cell membranes and membranes of hepatocyte organelles. Phospholipids regulate membrane permeability and the activity of membrane-bound enzymes, ensuring normal processes of oxidative phosphorylation. The drug normalizes the biosynthesis of phospholipids and general lipid metabolism in case of damage to hepatocytes of various etiologies. Restores hepatocyte membranes through structural regeneration and through competitive inhibition of oxidative processes: being embedded in biomembranes, unsaturated fatty acids are able to take on toxicogenic effects instead of membrane lipids. Promotes liver regeneration, stabilizes the physico-chemical properties of bile.


Indications for use

  • fatty liver degeneration of various etiologies, including diabetes mellitus;
  • chronic hepatitis;
  • cirrhosis of the liver;
  • alcohol and drug intoxication (as part of combination therapy);
  • poisoning (including medicinal);
  • dysfunction of hepatocytes (as a complication in other diseases);
  • damage to hepatocytes caused by exceeding the maximum permissible amounts of harmful substances in the environment, increased background radiation and exposure to other unfavorable environmental factors;
  • psoriasis (as part of combination therapy).





Directions for use and doses

Intravenous (IV) (slow) 250-500 mg (1-2 ampoules) (slow) is prescribed, in severe cases 0.5-1 g (2-4 ampoules) per day. The contents of two ampoules can be administered simultaneously.

Possible dilution in physiological solution 0.9% 200 ml, or glucose solution 5%, 10% 250 ml.

Use only clear solution. Do not mix with other medications in the same syringe. The IV administration technique should be strictly followed.

IV administration of the drug is recommended especially at the beginning of therapy in severe cases. It is recommended to supplement parenteral administration with oral administration of the drug as quickly as possible.

It is strictly contraindicated to inject Livson into a muscle (it can cause severe irritation).


Side effects

The drug is usually well tolerated.

From the digestive system:  rarely – a feeling of discomfort in the abdominal area.

A very rare hypersensitivity reaction to benzyl alcohol, which is part of the injection solution.



Hypersensitivity to the drug.

The solution for intravenous injection cannot be used to treat children under 3 years of age (due to the benzyl alcohol it contains).


Drug interactions

Drug interactions between the drug and other drugs have not been described.


special instructions

Use during pregnancy and lactation

There is not enough data on the effect of Livson on pregnancy and the child during breastfeeding. During pregnancy, the drug should be used only under medical supervision. When using Livson during lactation, breastfeeding should be stopped.

The drug should not be used after the expiration date and should be stored out of the reach of children.



Currently, no cases of drug overdose have been reported.


Release form

Solution for injection, 5 ml in ampoules. 10 ampoules along with instructions for use are placed in a cardboard box.


Food conditions

Store in a dry, cool place, at a temperature from 2 o C to 8 o C.


Best before date

3 years.


Conditions for dispensing from pharmacies

According to a doctor’s prescription.


Made in India

“Avison Pharmaceuticals Pvt. Ltd.”, India

“Adore Pharmaceuticals Pvt. Ltd.”, India,

(705472) 516 Khokani Ind Complex No 2

NR, Saibaba Temple, Sativali Vasai (E) – 401208